ADVIA 2120 CSF Assay
An Instant Hit
Another first, as Siemens Hematology debuts an FDA-cleared, automated CSF assay on a routine analyzer.
Performance Specifications
Reportable Results
- Automated WBC on all samples
- Automated RBC on samples <1,500 RBC/µL
- Differential, PMN, and MN (absolute and %) on samples with >20 WBC/µL
- WBC Differential includes: Neutrophils, Lymphocytes, Monocytes, Eosinophils*
Linearity
| Parameter | Range | Max. Deviation |
|---|---|---|
| WBC | 0-50/µL | 5 cells |
| 50-5,000/µL | 10% | |
| RBC | 0-50/µL | 5 cells |
| 50-1,500/µL | 10% |
Within Run Precision and Accuracy
(Nominal 100 cells/µL; 150 samples, at least 50% abnormal)
| Parameter | Stan. Dev./Bias | %CV/%Bias |
|---|---|---|
| WBC | 15 | 15% |
| RBC | 15 | 15% |
| #PMN | 20 | 20% |
| #MN | 20 | 20% |
Sample Stability
The prepared sample is stable between 4 minutes and 4 hours when stored at 18°-30°C.
Typical Cytograms (for illustrative purposes only)
CSF Assay Kit Components
CSF Assay Reagent Kit
1 bottle of reagent
- 25 aspirations
- 1-year shelf life (unopened)
- 30-day open bottle stability
- store at room temperature, 18°-30°C
CSF Assay Control Kit
2 levels: Low and High
- 1 vial of each level
- 10 aspirations/vial
- 105-day shelf life (unopened)
- 10-day open vial stability
- store refrigerated, 2°-8°C
Summary of ADVIA 2120 CSF Assay:
- Reduces manual, labor-intensive procedure, optimizing efficiency, productivity, and resource management.
- Improves turnaround time, providing critical results to clinicians for faster diagnosis and treatment.
- Allows results to be available 24 hours per day, regardless of staffing constraints.
- Increases consistency and confidence in results, minimizing technique variations between technologists.
- Provides QC for previously uncontrolled method.
- Expands platform for future development.
*For research use only.
